The goal of our research is to improve atomic level understanding of receptor-ligand interactions using computational models. Using physics-based methods such as molecular dynamics simulations and molecular docking, we focus on how small molecules interact with proteins and thereby modulate their function. In particular, we focus on membrane proteins such as G protein-coupled receptors (GPCRs).
We are part of the Dept. of Cell and Molecular Biology and the Science for Life Laboratory (SciLifeLab) at Uppsala university.